http://rdf.ncbi.nlm.nih.gov/pubmed/24497849

http://rdf.ncbi.nlm.nih.gov/pubmed/24497849

Jianquan. Chen, et.al., WNT7B promotes bone formation in part through mTORC1., PLoS genetics, 2014, 10

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm4(Wnt7b)Flng>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5613577
• Gt(ROSA)26Sor<tm5(Wnt5a)Flng>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5613578
• Tg(Runx2-rtTA*M2)#Flng
  http://metadb.riken.jp/db/mgi_rdf/MGI:5613580

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased bone mineral density_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Runx2-rtTA*M2)#Flng/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0000062I129C57BL6GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgRunx2rtTAM2Flng0TgtetOcre1Jaw0GtROSA26SorTgtetOcre1JawTgRunx2rtTAM2FlngGtROSA26Sortm4Wnt7bFlng
• increased bone mineral density_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0000062ICD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc
• increased bone mineral density_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0000062IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• abnormal bone marrow cavity morphology_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Rptor<tm1Rueg>/Rptor<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0000065I129S1Sv129X1SvJCD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorRptortm1RuegRptorTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngRptorGtROSA26SorRptortm1RuegTgSp7tTAtetOEGFPcre1Amc
• abnormal bone marrow cavity morphology_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0000065I129S1Sv129X1SvJCD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorRptortm1RuegRptortm1RuegTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1AmcRptortm1Rueg
• abnormal bone marrow cavity morphology_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0000065ICD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc
他30件を見る
• abnormal bone marrow cavity morphology_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0000065IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• abnormal chondrocyte morphology_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0000166ICD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc
• abnormal craniofacial morphology_Gt(ROSA)26Sor<tm5(Wnt5a)Flng>/?,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000428IC57BL6JCBAJGtROSA26Sortm5Wnt5aFlngTgWnt1cre11Rth0GtROSA26Sortm5Wnt5aFlngTgWnt1cre11Rth
• abnormal tibia morphology_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0000558IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• enlarged spleen_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0000691IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• abnormal long bone morphology_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0003723ICD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc
• abnormal bone structure_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Runx2-rtTA*M2)#Flng/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0003795I129C57BL6GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgRunx2rtTAM2Flng0TgtetOcre1Jaw0GtROSA26SorTgtetOcre1JawTgRunx2rtTAM2FlngGtROSA26Sortm4Wnt7bFlng
• abnormal bone structure_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0003795I129S1Sv129X1SvJCD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorRptortm1RuegRptortm1RuegTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1AmcRptortm1Rueg
• abnormal bone structure_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0003795ICD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc
• abnormal bone structure_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0003795IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• decreased length of long bones_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0004686ICD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc
• increased spleen weight_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0004952IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• decreased osteoclast cell number_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Runx2-rtTA*M2)#Flng/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0004985I129C57BL6GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgRunx2rtTAM2Flng0TgtetOcre1Jaw0GtROSA26SorTgtetOcre1JawTgRunx2rtTAM2FlngGtROSA26Sortm4Wnt7bFlng
• decreased osteoclast cell number_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0004985IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• increased osteoblast cell number_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Runx2-rtTA*M2)#Flng/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0004988I129C57BL6GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgRunx2rtTAM2Flng0TgtetOcre1Jaw0GtROSA26SorTgtetOcre1JawTgRunx2rtTAM2FlngGtROSA26Sortm4Wnt7bFlng
• increased osteoblast cell number_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0004988I129S1Sv129X1SvJCD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorRptortm1RuegRptortm1RuegTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1AmcRptortm1Rueg
• increased osteoblast cell number_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0004988ICD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc
• increased osteoblast cell number_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0004988IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• increased bone resorption_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0004992IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• increased bone mass_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Rptor<tm1Rueg>/Rptor<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0005605I129S1Sv129X1SvJCD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorRptortm1RuegRptorTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngRptorGtROSA26SorRptortm1RuegTgSp7tTAtetOEGFPcre1Amc
• increased bone mass_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
  http://metadb.riken.jp/0005605ICD1GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc0GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgSp7tTAtetOEGFPcre1Amc
• increased bone mass_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0005605IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• embryonic lethality_Gt(ROSA)26Sor<tm5(Wnt5a)Flng>/?,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0008762IC57BL6JCBAJGtROSA26Sortm5Wnt5aFlngTgWnt1cre11Rth0GtROSA26Sortm5Wnt5aFlngTgWnt1cre11Rth
• increased trabecular bone mass_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Runx2-rtTA*M2)#Flng/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0010872I129C57BL6GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgRunx2rtTAM2Flng0TgtetOcre1Jaw0GtROSA26SorTgtetOcre1JawTgRunx2rtTAM2FlngGtROSA26Sortm4Wnt7bFlng
• increased trabecular bone volume_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Runx2-rtTA*M2)#Flng/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0010878I129C57BL6GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgRunx2rtTAM2Flng0TgtetOcre1Jaw0GtROSA26SorTgtetOcre1JawTgRunx2rtTAM2FlngGtROSA26Sortm4Wnt7bFlng
• increased trabecular bone volume_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0010878IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• decreased trabecular bone volume_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0010879IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• abnormal circulating osteocalcin level_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0011922IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor
• increased bone ossification_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Runx2-rtTA*M2)#Flng/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0020039I129C57BL6GtROSA26Sortm4Wnt7bFlngGtROSA26SorTgRunx2rtTAM2Flng0TgtetOcre1Jaw0GtROSA26SorTgtetOcre1JawTgRunx2rtTAM2FlngGtROSA26Sortm4Wnt7bFlng
• increased bone ossification_Gt(ROSA)26Sor<tm4(Wnt7b)Flng>/Gt(ROSA)26Sor<+>,Tg(Col1a1-cre)1Ack/0
  http://metadb.riken.jp/0020039IFVBNGtROSA26Sortm4Wnt7bFlngGtROSA26SorTgCol1a1cre1Ack0TgCol1a1cre1AckGtROSA26Sortm4Wnt7bFlngGtROSA26Sor

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm4(Wnt7b)Flng>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5613577
• Gt(ROSA)26Sor<tm5(Wnt5a)Flng>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5613578
• Tg(Runx2-rtTA*M2)#Flng
  http://metadb.riken.jp/db/mgi_rdf/MGI:5613580