increased B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Mirc30<tm1.1Rdf>/Mirc30<tm1.1Rdf>

http://metadb.riken.jp/0005014I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Cd19tm1creCgnCd19Mirc30tm11RdfMirc30tm11RdfCd19tm1creCgnMirc30tm11RdfCd19

increased B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Mirc30<tm1.1Rdf>/Mirc30<tm1.1Rdf>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• microRNA cluster 30, including Mir16-1 through Mir15a
  http://metadb.riken.jp/db/mgi_rdf/MGI:5315448

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd19<tm1(cre)Cgn>/Cd19<+>,Mirc30<tm1.1Rdf>/Mirc30<tm1.1Rdf>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<tm1(cre)Cgn>|Mirc30<tm1.1Rdf>|Cd19<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased B cell number
  http://purl.obolibrary.org/obo/MP_0005014

文献

http://purl.org/net/cito/citesAsAuthority

• Ulf. Klein, et.al., The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia., Cancer cell, 2010, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/20060366