increased B cell number_Foxo1<tm1Rdp>/Foxo1<tm1.1Rdp>,Igh-J<tm1Cgn>/Igh<tm4Cgn>,Tg(Cr2-cre)3Cgn/0

http://metadb.riken.jp/0005014I129P2OlaHsd129S1SvFoxo1tm1RdpFoxo1tm11RdpIghJtm1CgnIghtm4CgnTgCr2cre3Cgn0Foxo1tm1RdpIghJtm1CgnIghtm4CgnFoxo1tm11RdpTgCr2cre3Cgn

increased B cell number_Foxo1<tm1Rdp>/Foxo1<tm1.1Rdp>,Igh-J<tm1Cgn>/Igh<tm4Cgn>,Tg(Cr2-cre)3Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442
• forkhead box O1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890077
• transgene insertion 3, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:3708319
• immunoglobulin heavy chain, joining region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96461

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxo1<tm1Rdp>/Foxo1<tm1.1Rdp>,Igh-J<tm1Cgn>/Igh<tm4Cgn>,Tg(Cr2-cre)3Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Foxo1<tm1Rdp>|Igh-J<tm1Cgn>|Igh<tm4Cgn>|Foxo1<tm1.1Rdp>|Tg(Cr2-cre)3Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased B cell number
  http://purl.obolibrary.org/obo/MP_0005014

文献

http://purl.org/net/cito/citesAsAuthority

• Lakshmi. Srinivasan, et.al., PI3 kinase signals BCR-dependent mature B cell survival., Cell, 2009, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/19879843