increased T cell number_Casp8<tm1.1Raz>/Casp8<tm1.1Raz>,Ripk3<tm1Vmd>/Ripk3<tm1Vmd>

http://metadb.riken.jp/0005015I129P2OlaHsd129S1Sv129X1SvJCasp8tm11RazCasp8tm11RazRipk3tm1VmdRipk3tm1VmdRipk3tm1VmdCasp8tm11Raz

increased T cell number_Casp8<tm1.1Raz>/Casp8<tm1.1Raz>,Ripk3<tm1Vmd>/Ripk3<tm1Vmd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• caspase 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:1261423
• receptor-interacting serine-threonine kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2154952

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Casp8<tm1.1Raz>/Casp8<tm1.1Raz>,Ripk3<tm1Vmd>/Ripk3<tm1Vmd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ripk3<tm1Vmd>|Casp8<tm1.1Raz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell number
  http://purl.obolibrary.org/obo/MP_0005015

文献

http://purl.org/net/cito/citesAsAuthority

• Andrew. Oberst, et.al., Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis., Nature, 2011, 471
  http://rdf.ncbi.nlm.nih.gov/pubmed/21368763
• William J. Kaiser, et.al., RIP3 mediates the embryonic lethality of caspase-8-deficient mice., Nature, 2011, 471
  http://rdf.ncbi.nlm.nih.gov/pubmed/21368762