decreased B cell number_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0

http://metadb.riken.jp/0005017I129S1Sv129X1SvJC57BL6Ezh1tm1SgonEzh1tm1SgonTgVav1cre1Graf0TgVav1cre1GrafEzh1tm1Sgon

decreased B cell number_Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Thomas Graf
  http://metadb.riken.jp/db/mgi_rdf/MGI:3765352
• enhancer of zeste 1 polycomb repressive complex 2 subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:1097695

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ezh1<tm1Sgon>/Ezh1<tm1Sgon>,Tg(Vav1-cre)1Graf/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vav1-cre)1Graf|Ezh1<tm1Sgon>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B cell number
  http://purl.obolibrary.org/obo/MP_0005017

文献

http://purl.org/net/cito/citesAsAuthority

• Isabel. Hidalgo, et.al., Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest., Cell stem cell, 2012, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/23122289