decreased T cell number_Cops8<tm1Nwe>/Cops8<tm1.1Nwe>,Tg(Cd4-cre)1Cwi/?

http://metadb.riken.jp/0005018I129S1SvC57BL6DBA2Cops8tm1NweCops8tm11NweTgCd4cre1CwiCops8tm11NweTgCd4cre1CwiCops8tm1Nwe

decreased T cell number_Cops8<tm1Nwe>/Cops8<tm1.1Nwe>,Tg(Cd4-cre)1Cwi/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• COP9 signalosome subunit 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:1915363
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cops8<tm1Nwe>/Cops8<tm1.1Nwe>,Tg(Cd4-cre)1Cwi/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cops8<tm1.1Nwe>|Tg(Cd4-cre)1Cwi|Cops8<tm1Nwe>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T cell number
  http://purl.obolibrary.org/obo/MP_0005018

文献

http://purl.org/net/cito/citesAsAuthority

• Suchithra. Menon, et.al., COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence., Nature immunology, 2007, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/17906629