Suchithra. Menon, et.al., COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence., Nature immunology, 2007, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/17906629

Suchithra. Menon, et.al., COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence., Nature immunology, 2007, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cops8<tm1.1Nwe>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3762120
• Cops8<tm1Nwe>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3762119

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased embryo size_Cops8<tm1.1Nwe>/Cops8<tm1.1Nwe>
  http://metadb.riken.jp/0001698IC57BL6Cops8tm11NweCops8tm11NweCops8tm11Nwe
• decreased T cell proliferation_Cops8<tm1Nwe>/Cops8<tm1.1Nwe>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0005095I129S1SvC57BL6DBA2Cops8tm1NweCops8tm11NweTgCd4cre1CwiCops8tm11NweTgCd4cre1CwiCops8tm1Nwe
• abnormal inner cell mass proliferation_Cops8<tm1.1Nwe>/Cops8<tm1.1Nwe>
  http://metadb.riken.jp/0004966IC57BL6Cops8tm11NweCops8tm11NweCops8tm11Nwe
• prenatal lethality, complete penetrance_Cops8<tm1.1Nwe>/Cops8<tm1.1Nwe>
  http://metadb.riken.jp/0011091IC57BL6Cops8tm11NweCops8tm11NweCops8tm11Nwe
• abnormal CD4-positive, alpha-beta T cell physiology_Cops8<tm1Nwe>/Cops8<tm1.1Nwe>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0005463I129S1SvC57BL6DBA2Cops8tm1NweCops8tm11NweTgCd4cre1CwiCops8tm11NweTgCd4cre1CwiCops8tm1Nwe
• abnormal cell cycle_Cops8<tm1Nwe>/Cops8<tm1.1Nwe>
  http://metadb.riken.jp/0003077I129S1SvC57BL6Cops8tm1NweCops8tm11NweCops8tm1NweCops8tm11Nwe
• decreased interleukin-2 secretion_Cops8<tm1Nwe>/Cops8<tm1.1Nwe>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0008688I129S1SvC57BL6DBA2Cops8tm1NweCops8tm11NweTgCd4cre1CwiCops8tm11NweTgCd4cre1CwiCops8tm1Nwe
• abnormal T cell activation_Cops8<tm1Nwe>/Cops8<tm1.1Nwe>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0001828I129S1SvC57BL6DBA2Cops8tm1NweCops8tm11NweTgCd4cre1CwiCops8tm11NweTgCd4cre1CwiCops8tm1Nwe
• decreased T cell number_Cops8<tm1Nwe>/Cops8<tm1.1Nwe>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0005018I129S1SvC57BL6DBA2Cops8tm1NweCops8tm11NweTgCd4cre1CwiCops8tm11NweTgCd4cre1CwiCops8tm1Nwe
• embryonic growth retardation_Cops8<tm1.1Nwe>/Cops8<tm1.1Nwe>
  http://metadb.riken.jp/0003984IC57BL6Cops8tm11NweCops8tm11NweCops8tm11Nwe

class

http://purl.org/net/cito/citesAsAuthority

• Cops8<tm1.1Nwe>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3762120
• Cops8<tm1Nwe>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3762119

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD15231
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15231
• CD20086
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD20086