decreased T cell number_Vav1<tm1Tyb>/Vav1<tm1Tyb>,Vav3<tm1Swat>/Vav3<tm1Swat>

http://metadb.riken.jp/0005018I129S2SvPas129S6SvEvTacC57BL6Vav1tm1TybVav1tm1TybVav3tm1SwatVav3tm1SwatVav3tm1SwatVav1tm1Tyb

decreased T cell number_Vav1<tm1Tyb>/Vav1<tm1Tyb>,Vav3<tm1Swat>/Vav3<tm1Swat>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• vav 3 oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:1888518
• vav 1 oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:98923

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Vav1<tm1Tyb>/Vav1<tm1Tyb>,Vav3<tm1Swat>/Vav3<tm1Swat>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Vav3<tm1Swat>|Vav1<tm1Tyb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T cell number
  http://purl.obolibrary.org/obo/MP_0005018

文献

http://purl.org/net/cito/citesAsAuthority

• Keiko. Fujikawa, et.al., Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells., The Journal of experimental medicine, 2003, 198
  http://rdf.ncbi.nlm.nih.gov/pubmed/14623913