accumulation of giant lysosomes in kidney/renal tubule cells_Clcn5<tm1Tjj>/Clcn5<+>,Clcn7<tm3.1Tjj>/Clcn7<tm3.1Tjj>,Tg(APOE-cre)VITew/0

http://metadb.riken.jp/0005060I129Sv129S1Sv129X1SvJC57BL6C57BL6JClcn5tm1TjjClcn5Clcn7tm31TjjClcn7tm31TjjTgAPOEcreVITew0TgAPOEcreVITewClcn5tm1TjjClcn7tm31TjjClcn5

accumulation of giant lysosomes in kidney/renal tubule cells_Clcn5<tm1Tjj>/Clcn5<+>,Clcn7<tm3.1Tjj>/Clcn7<tm3.1Tjj>,Tg(APOE-cre)VITew/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• chloride channel, voltage-sensitive 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1347048
• transgene insertion VI, Thomas E Willnow
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450252
• chloride channel, voltage-sensitive 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:99486

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Clcn5<tm1Tjj>/Clcn5<+>,Clcn7<tm3.1Tjj>/Clcn7<tm3.1Tjj>,Tg(APOE-cre)VITew/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(APOE-cre)VITew|Clcn5<tm1Tjj>|Clcn7<tm3.1Tjj>|Clcn5<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• accumulation of giant lysosomes in kidney/renal tubule cells
  http://purl.obolibrary.org/obo/MP_0005060

文献

http://purl.org/net/cito/citesAsAuthority

• Lena. Wartosch, et.al., Lysosomal degradation of endocytosed proteins depends on the chloride transport protein ClC-7., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2009, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/19661288