impaired granulocyte bactericidal activity_Syk<tm1Tyb>/Syk<tm1.2Tara>,Tg(S100A8-cre,-EGFP)1Ilw/0

http://metadb.riken.jp/0005074I129P2OlaHsd129S2SvPasC3HC57BL6Syktm1TybSyktm12TaraTgS100A8creEGFP1Ilw0Syktm12TaraTgS100A8creEGFP1IlwSyktm1Tyb

impaired granulocyte bactericidal activity_Syk<tm1Tyb>/Syk<tm1.2Tara>,Tg(S100A8-cre,-EGFP)1Ilw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1,Irving L Weissman
  http://metadb.riken.jp/db/mgi_rdf/MGI:4415243
• spleen tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99515

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Syk<tm1Tyb>/Syk<tm1.2Tara>,Tg(S100A8-cre,-EGFP)1Ilw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Syk<tm1.2Tara>|Tg(S100A8-cre,-EGFP)1Ilw|Syk<tm1Tyb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * C3H * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired granulocyte bactericidal activity
  http://purl.obolibrary.org/obo/MP_0005074

文献

http://purl.org/net/cito/citesAsAuthority

• Jessica A. Van Ziffle, et.al., Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection., Blood, 2009, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/19797524