decreased double-negative T cell number_Cpa3<tm3(icre)Hrr>/Cpa3<+>,Notch1<tm1Agt>/Notch1<tm1Agt>

http://metadb.riken.jp/0005089I129C57BL6Cpa3tm3icreHrrCpa3Notch1tm1AgtNotch1tm1AgtNotch1tm1AgtCpa3Cpa3tm3icreHrr

decreased double-negative T cell number_Cpa3<tm3(icre)Hrr>/Cpa3<+>,Notch1<tm1Agt>/Notch1<tm1Agt>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• notch 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97363
• carboxypeptidase A3, mast cell
  http://metadb.riken.jp/db/mgi_rdf/MGI:88479

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cpa3<tm3(icre)Hrr>/Cpa3<+>,Notch1<tm1Agt>/Notch1<tm1Agt>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Notch1<tm1Agt>|Cpa3<+>|Cpa3<tm3(icre)Hrr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-negative T cell number
  http://purl.obolibrary.org/obo/MP_0005089

文献

http://purl.org/net/cito/citesAsAuthority

• Thorsten B. Feyerabend, et.al., Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms., Immunity, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19110448