Thorsten B. Feyerabend, et.al., Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms., Immunity, 2009, 30

http://rdf.ncbi.nlm.nih.gov/pubmed/19110448

Thorsten B. Feyerabend, et.al., Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms., Immunity, 2009, 30

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cpa3<tm3(icre)Hrr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829878

class

http://purl.org/net/cito/citesAsAuthority

• Cpa3<tm3(icre)Hrr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829878

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased double-negative T cell number_Cpa3<tm3(icre)Hrr>/Cpa3<+>,Notch1<tm1Agt>/Notch1<tm1Agt>
  http://metadb.riken.jp/0005089I129C57BL6Cpa3tm3icreHrrCpa3Notch1tm1AgtNotch1tm1AgtNotch1tm1AgtCpa3Cpa3tm3icreHrr
• abnormal B cell morphology_Cpa3<tm3(icre)Hrr>/Cpa3<+>,Notch1<tm1Agt>/Notch1<tm1Agt>
  http://metadb.riken.jp/0004939I129C57BL6Cpa3tm3icreHrrCpa3Notch1tm1AgtNotch1tm1AgtNotch1tm1AgtCpa3Cpa3tm3icreHrr
• abnormal T cell receptor beta chain V(D)J recombination_Cpa3<tm3(icre)Hrr>/Cpa3<+>,Gt(ROSA)26Sor<tm1Hjf>/?,Notch1<tm1Agt>/Notch1<tm1Agt>
  http://metadb.riken.jp/0008758I129C57BL6Cpa3tm3icreHrrCpa3GtROSA26Sortm1HjfNotch1tm1AgtNotch1tm1AgtCpa3Cpa3tm3icreHrrGtROSA26Sortm1HjfNotch1tm1Agt
• decreased double-positive T cell number_Cpa3<tm3(icre)Hrr>/Cpa3<+>,Notch1<tm1Agt>/Notch1<tm1Agt>
  http://metadb.riken.jp/0005092I129C57BL6Cpa3tm3icreHrrCpa3Notch1tm1AgtNotch1tm1AgtNotch1tm1AgtCpa3Cpa3tm3icreHrr
• abnormal T cell receptor beta chain V(D)J recombination_Cpa3<tm3(icre)Hrr>/Cpa3<+>,Notch1<tm1Agt>/Notch1<tm1Agt>
  http://metadb.riken.jp/0008758I129C57BL6Cpa3tm3icreHrrCpa3Notch1tm1AgtNotch1tm1AgtNotch1tm1AgtCpa3Cpa3tm3icreHrr
• abnormal B cell differentiation_Cpa3<tm3(icre)Hrr>/Cpa3<+>,Notch1<tm1Agt>/Notch1<tm1Agt>
  http://metadb.riken.jp/0002144I129C57BL6Cpa3tm3icreHrrCpa3Notch1tm1AgtNotch1tm1AgtNotch1tm1AgtCpa3Cpa3tm3icreHrr
• increased single-positive T cell number_Cpa3<tm3(icre)Hrr>/Cpa3<+>,Notch1<tm1Agt>/Notch1<tm1Agt>
  http://metadb.riken.jp/0008082I129C57BL6Cpa3tm3icreHrrCpa3Notch1tm1AgtNotch1tm1AgtNotch1tm1AgtCpa3Cpa3tm3icreHrr
• thymus hypoplasia_Cpa3<tm3(icre)Hrr>/Cpa3<+>,Notch1<tm1Agt>/Notch1<tm1Agt>
  http://metadb.riken.jp/0001823I129C57BL6Cpa3tm3icreHrrCpa3Notch1tm1AgtNotch1tm1AgtNotch1tm1AgtCpa3Cpa3tm3icreHrr
• abnormal dendritic cell differentiation_Cpa3<tm3(icre)Hrr>/Cpa3<+>,Gt(ROSA)26Sor<tm1Hjf>/?,Notch1<tm1Agt>/Notch1<tm1Agt>
  http://metadb.riken.jp/0008115I129C57BL6Cpa3tm3icreHrrCpa3GtROSA26Sortm1HjfNotch1tm1AgtNotch1tm1AgtCpa3Cpa3tm3icreHrrGtROSA26Sortm1HjfNotch1tm1Agt

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD39446
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39446