decreased double-negative T cell number_Vav1<tm1Tyb>/Vav1<tm1Tyb>,Vav2<tm1Kdf>/Vav2<tm1Kdf>

http://metadb.riken.jp/0005089I129S1Sv129S2SvPasVav1tm1TybVav1tm1TybVav2tm1KdfVav2tm1KdfVav1tm1TybVav2tm1Kdf

decreased double-negative T cell number_Vav1<tm1Tyb>/Vav1<tm1Tyb>,Vav2<tm1Kdf>/Vav2<tm1Kdf>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• vav 2 oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:102718
• vav 1 oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:98923

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Vav1<tm1Tyb>/Vav1<tm1Tyb>,Vav2<tm1Kdf>/Vav2<tm1Kdf>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Vav1<tm1Tyb>|Vav2<tm1Kdf>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-negative T cell number
  http://purl.obolibrary.org/obo/MP_0005089

文献

http://purl.org/net/cito/citesAsAuthority

• Keiko. Fujikawa, et.al., Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells., The Journal of experimental medicine, 2003, 198
  http://rdf.ncbi.nlm.nih.gov/pubmed/14623913