decreased double-negative T cell number_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>

http://metadb.riken.jp/0005089I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW

decreased double-negative T cell number_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• FMS-like tyrosine kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:95559
• KIT proto-oncogene receptor tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96677

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kit<W-v>|Flt3<tm1Irl>|Kit<W>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-negative T cell number
  http://purl.obolibrary.org/obo/MP_0005089

文献

http://purl.org/net/cito/citesAsAuthority

• K. Mackarehtschian, et.al., Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors., Immunity, 1995, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/7621074