K. Mackarehtschian, et.al., Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors., Immunity, 1995, 3

http://rdf.ncbi.nlm.nih.gov/pubmed/7621074

K. Mackarehtschian, et.al., Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors., Immunity, 1995, 3

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Flt3<tm1Irl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384051

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal B cell differentiation_Flt3<tm1Irl>/Flt3<tm1Irl>
  http://metadb.riken.jp/0002144E129SSvEvFlt3tm1IrlorI129SSvEvC57BL6JFlt3tm1IrlFlt3tm1IrlFlt3tm1Irl
• abnormal blood cell morphology/development_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0002429I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• decreased pro-B cell number_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0008208I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• decreased double-negative T cell number_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0005089I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• decreased pre-B cell number_Flt3<tm1Irl>/Flt3<tm1Irl>
  http://metadb.riken.jp/0008209E129SSvEvFlt3tm1IrlorI129SSvEvC57BL6JFlt3tm1IrlFlt3tm1IrlFlt3tm1Irl
• decreased body weight_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0001262I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• decreased B cell number_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0005017I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• thymus hypoplasia_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0001823I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• decreased double-positive T cell number_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0005092I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• abnormal T cell number_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0006387I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• decreased pro-B cell number_Flt3<tm1Irl>/Flt3<tm1Irl>
  http://metadb.riken.jp/0008208E129SSvEvFlt3tm1IrlorI129SSvEvC57BL6JFlt3tm1IrlFlt3tm1IrlFlt3tm1Irl
• abnormal leukocyte morphology_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0008246I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• abnormal common myeloid progenitor cell morphology_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0006410I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• abnormal myelopoiesis_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0001601I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• decreased bone marrow cell number_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0000333I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• decreased pre-B cell number_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0008209I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW
• decreased lymphocyte cell number_Flt3<tm1Irl>/Flt3<tm1Irl>,Kit<W>/Kit<W-v>
  http://metadb.riken.jp/0005016I129SSvEvC57BL6Flt3tm1IrlFlt3tm1IrlKitWKitWvKitWvFlt3tm1IrlKitW

class

http://purl.org/net/cito/citesAsAuthority

• Flt3<tm1Irl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384051