decreased double-negative T cell number_Mcl1<tm2Sjk>/Mcl1<tm3Sjk>,Tg(Lck-cre)1Cwi/0

http://metadb.riken.jp/0005089I129X1SvJC57BL6DBA2Mcl1tm2SjkMcl1tm3SjkTgLckcre1Cwi0Mcl1tm3SjkMcl1tm2SjkTgLckcre1Cwi

decreased double-negative T cell number_Mcl1<tm2Sjk>/Mcl1<tm3Sjk>,Tg(Lck-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448687
• myeloid cell leukemia sequence 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:101769

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mcl1<tm2Sjk>/Mcl1<tm3Sjk>,Tg(Lck-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mcl1<tm3Sjk>|Mcl1<tm2Sjk>|Tg(Lck-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-negative T cell number
  http://purl.obolibrary.org/obo/MP_0005089

文献

http://purl.org/net/cito/citesAsAuthority

• Joseph T. Opferman, et.al., Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1., Nature, 2003, 426
  http://rdf.ncbi.nlm.nih.gov/pubmed/14668867