decreased double-positive T cell number_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>,Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0005092I129C57BL6CBACcnd3tm1PiscCcnd3tm1PiscRb1tm2BrnRb1tm2BrnTgMx1cre1Cgn0Rb1tm2BrnTgMx1cre1CgnCcnd3tm1Pisc

decreased double-positive T cell number_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>,Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin D3
  http://metadb.riken.jp/db/mgi_rdf/MGI:88315
• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>,Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rb1<tm2Brn>|Tg(Mx1-cre)1Cgn|Ccnd3<tm1Pisc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• Catherine M. Sawai, et.al., Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia., Cancer cell, 2012, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/23079656