Catherine M. Sawai, et.al., Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia., Cancer cell, 2012, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/23079656

Catherine M. Sawai, et.al., Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia., Cancer cell, 2012, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ccnd3<tm1.1(Ccnd2)Iaai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5468556

class

http://purl.org/net/cito/citesAsAuthority

• Ccnd3<tm1.1(Ccnd2)Iaai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5468556

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased T cell proliferation_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>,Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0005095I129S4SvJaeSorCcnd3tm1PiscCcnd3tm1PiscCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1MlfCcnd3tm1Pisc
• decreased B cell proliferation_Ccnd3<tm1.1(Ccnd2)Iaai>/Ccnd3<tm1.1(Ccnd2)Iaai>
  http://metadb.riken.jp/0005093I129S6SvEvTacCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2Iaai
• decreased double-positive T cell number_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>,Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005092I129C57BL6CBACcnd3tm1PiscCcnd3tm1PiscRb1tm2BrnRb1tm2BrnTgMx1cre1Cgn0Rb1tm2BrnTgMx1cre1CgnCcnd3tm1Pisc
• decreased double-positive T cell number_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>
  http://metadb.riken.jp/0005092NSCcnd3tm1PiscCcnd3tm1PiscCcnd3tm1Pisc
• decreased B cell proliferation_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>
  http://metadb.riken.jp/0005093NSCcnd3tm1PiscCcnd3tm1PiscCcnd3tm1Pisc
• abnormal bone marrow cell physiology_Ccnd3<tm1.1(Ccnd2)Iaai>/Ccnd3<tm1.1(Ccnd2)Iaai>
  http://metadb.riken.jp/0009278I129S6SvEvTacCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2Iaai
• decreased bone marrow cell number_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>
  http://metadb.riken.jp/0000333NSCcnd3tm1PiscCcnd3tm1PiscCcnd3tm1Pisc
• decreased double-positive T cell number_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>,Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0005092I129S4SvJaeSorCcnd3tm1PiscCcnd3tm1PiscCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1MlfCcnd3tm1Pisc
• decreased pre-B cell number_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>
  http://metadb.riken.jp/0008209NSCcnd3tm1PiscCcnd3tm1PiscCcnd3tm1Pisc
• decreased bone marrow cell number_Ccnd3<tm1.1(Ccnd2)Iaai>/Ccnd3<tm1.1(Ccnd2)Iaai>
  http://metadb.riken.jp/0000333I129S6SvEvTacCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2Iaai
• decreased pre-B cell number_Ccnd3<tm1.1(Ccnd2)Iaai>/Ccnd3<tm1.1(Ccnd2)Iaai>
  http://metadb.riken.jp/0008209I129S6SvEvTacCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2Iaai
• abnormal bone marrow cell physiology_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>,Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0009278I129S4SvJaeSorCcnd3tm1PiscCcnd3tm1PiscCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1MlfCcnd3tm1Pisc
• small thymus_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>
  http://metadb.riken.jp/0000706NSCcnd3tm1PiscCcnd3tm1PiscCcnd3tm1Pisc
• thymus hypoplasia_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>,Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>
  http://metadb.riken.jp/0001823I129S4SvJaeSorCcnd3tm1PiscCcnd3tm1PiscCdkn1btm1MlfCdkn1btm1MlfCdkn1btm1MlfCcnd3tm1Pisc
• small thymus_Ccnd3<tm1.1(Ccnd2)Iaai>/Ccnd3<tm1.1(Ccnd2)Iaai>
  http://metadb.riken.jp/0000706I129S6SvEvTacCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2Iaai
• decreased T cell proliferation_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>
  http://metadb.riken.jp/0005095NSCcnd3tm1PiscCcnd3tm1PiscCcnd3tm1Pisc
• decreased T cell proliferation_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>,Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005095I129C57BL6CBACcnd3tm1PiscCcnd3tm1PiscRb1tm2BrnRb1tm2BrnTgMx1cre1Cgn0Rb1tm2BrnTgMx1cre1CgnCcnd3tm1Pisc
• thymus hypoplasia_Ccnd3<tm1.1(Ccnd2)Iaai>/Ccnd3<tm1.1(Ccnd2)Iaai>
  http://metadb.riken.jp/0001823I129S6SvEvTacCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2Iaai
• decreased T cell proliferation_Ccnd3<tm1.1(Ccnd2)Iaai>/Ccnd3<tm1.1(Ccnd2)Iaai>
  http://metadb.riken.jp/0005095I129S6SvEvTacCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2Iaai
• thymus hypoplasia_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>,Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001823I129C57BL6CBACcnd3tm1PiscCcnd3tm1PiscRb1tm2BrnRb1tm2BrnTgMx1cre1Cgn0Rb1tm2BrnTgMx1cre1CgnCcnd3tm1Pisc
• decreased double-positive T cell number_Ccnd3<tm1.1(Ccnd2)Iaai>/Ccnd3<tm1.1(Ccnd2)Iaai>
  http://metadb.riken.jp/0005092I129S6SvEvTacCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2IaaiCcnd3tm11Ccnd2Iaai
• thymus hypoplasia_Ccnd3<tm1Pisc>/Ccnd3<tm1Pisc>
  http://metadb.riken.jp/0001823NSCcnd3tm1PiscCcnd3tm1PiscCcnd3tm1Pisc