decreased double-positive T cell number_Adam10<tm1Zhu>/Adam10<tm1.1Zhu>,Tg(Lck-cre)#Zhu/0

http://metadb.riken.jp/0005092I129S6SvEvTacC57BL6SJLSJLJAdam10tm1ZhuAdam10tm11ZhuTgLckcreZhu0Adam10tm1ZhuAdam10tm11ZhuTgLckcreZhu

decreased double-positive T cell number_Adam10<tm1Zhu>/Adam10<tm1.1Zhu>,Tg(Lck-cre)#Zhu/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Yuan Zhuang
  http://metadb.riken.jp/db/mgi_rdf/MGI:3054842
• a disintegrin and metallopeptidase domain 10
  http://metadb.riken.jp/db/mgi_rdf/MGI:109548

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Adam10<tm1Zhu>/Adam10<tm1.1Zhu>,Tg(Lck-cre)#Zhu/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Adam10<tm1Zhu>|Adam10<tm1.1Zhu>|Tg(Lck-cre)#Zhu

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * SJL * SJL/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• Lei. Tian, et.al., ADAM10 is essential for proteolytic activation of Notch during thymocyte development., International immunology, 2008, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/18635581