decreased double-positive T cell number_Kmt5b<tm1Jnw>/Kmt5b<tm1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>,Tg(Vav1-icre)A2Kio/0

http://metadb.riken.jp/0005092I129SvC57BL6JC57BL10CBACaKmt5btm1JnwKmt5btm1JnwKmt5ctm11JnwKmt5ctm11JnwTgVav1icreA2Kio0Kmt5ctm11JnwKmt5btm1JnwTgVav1icreA2Kio

decreased double-positive T cell number_Kmt5b<tm1Jnw>/Kmt5b<tm1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>,Tg(Vav1-icre)A2Kio/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion A2, Dimitris Kioussis
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449945
• lysine methyltransferase 5B
  http://metadb.riken.jp/db/mgi_rdf/MGI:2444557
• lysine methyltransferase 5C
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385262

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kmt5b<tm1Jnw>/Kmt5b<tm1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>,Tg(Vav1-icre)A2Kio/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kmt5c<tm1.1Jnw>|Kmt5b<tm1Jnw>|Tg(Vav1-icre)A2Kio

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * C57BL/10 * CBA/Ca

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• Gunnar. Schotta, et.al., A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse., Genes & development, 2008, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/18676810