Gunnar. Schotta, et.al., A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse., Genes & development, 2008, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/18676810

Gunnar. Schotta, et.al., A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse., Genes & development, 2008, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Kmt5b<tm1.1Jnw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810075
• Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810079
• Kmt5c<tm1Jnw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810076
• Kmt5b<tm1Jnw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810074

class

http://purl.org/net/cito/citesAsAuthority

• Kmt5b<tm1.1Jnw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810075
• Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810079
• Kmt5c<tm1Jnw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810076
• Kmt5b<tm1Jnw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810074

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body size_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/0001265I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5ctm11JnwKmt5ctm11JnwKmt5btm11JnwKmt5ctm11Jnw
• abnormal lymphopoiesis_Kmt5b<tm1Jnw>/Kmt5b<tm1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0002401I129SvC57BL6JC57BL10CBACaKmt5btm1JnwKmt5btm1JnwKmt5ctm11JnwKmt5ctm11JnwTgVav1icreA2Kio0Kmt5ctm11JnwKmt5btm1JnwTgVav1icreA2Kio
• prenatal lethality, incomplete penetrance_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>
  http://metadb.riken.jp/0011101I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5btm11Jnw
• increased cellular sensitivity to hydroxyurea_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/0008409I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5ctm11JnwKmt5ctm11JnwKmt5btm11JnwKmt5ctm11Jnw
• abnormal DNA repair_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/0008058I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5ctm11JnwKmt5ctm11JnwKmt5btm11JnwKmt5ctm11Jnw
• early cellular replicative senescence_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/0008008I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5ctm11JnwKmt5ctm11JnwKmt5btm11JnwKmt5ctm11Jnw
• abnormal cell cycle_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/0003077I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5ctm11JnwKmt5ctm11JnwKmt5btm11JnwKmt5ctm11Jnw
• prenatal lethality, incomplete penetrance_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/0011101I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5ctm11JnwKmt5ctm11JnwKmt5btm11JnwKmt5ctm11Jnw
• decreased body size_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>
  http://metadb.riken.jp/0001265I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5btm11Jnw
• decreased fibroblast proliferation_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/0011704I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5ctm11JnwKmt5ctm11JnwKmt5btm11JnwKmt5ctm11Jnw
• decreased B cell number_Kmt5b<tm1Jnw>/Kmt5b<tm1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0005017I129SvC57BL6JC57BL10CBACaKmt5btm1JnwKmt5btm1JnwKmt5ctm11JnwKmt5ctm11JnwTgVav1icreA2Kio0Kmt5ctm11JnwKmt5btm1JnwTgVav1icreA2Kio
• neonatal lethality, complete penetrance_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>
  http://metadb.riken.jp/0011087I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5btm11Jnw
• no abnormal phenotype detected_Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/0002169I129C57BL6JKmt5ctm11JnwKmt5ctm11JnwKmt5ctm11Jnw
• decreased double-positive T cell number_Kmt5b<tm1Jnw>/Kmt5b<tm1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0005092I129SvC57BL6JC57BL10CBACaKmt5btm1JnwKmt5btm1JnwKmt5ctm11JnwKmt5ctm11JnwTgVav1icreA2Kio0Kmt5ctm11JnwKmt5btm1JnwTgVav1icreA2Kio
• increased cellular sensitivity to ultraviolet irradiation_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/0008410I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5ctm11JnwKmt5ctm11JnwKmt5btm11JnwKmt5ctm11Jnw
• neonatal lethality, complete penetrance_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/0011087I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5ctm11JnwKmt5ctm11JnwKmt5btm11JnwKmt5ctm11Jnw
• abnormal pulmonary alveolus morphology_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>
  http://metadb.riken.jp/0002270I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5btm11Jnw
• abnormal pulmonary alveolus morphology_Kmt5b<tm1.1Jnw>/Kmt5b<tm1.1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>
  http://metadb.riken.jp/0002270I129C57BL6JKmt5btm11JnwKmt5btm11JnwKmt5ctm11JnwKmt5ctm11JnwKmt5btm11JnwKmt5ctm11Jnw
• abnormal class switch recombination_Kmt5b<tm1Jnw>/Kmt5b<tm1Jnw>,Kmt5c<tm1.1Jnw>/Kmt5c<tm1.1Jnw>,Tg(Vav1-icre)A2Kio/0
  http://metadb.riken.jp/0004816I129SvC57BL6JC57BL10CBACaKmt5btm1JnwKmt5btm1JnwKmt5ctm11JnwKmt5ctm11JnwTgVav1icreA2Kio0Kmt5ctm11JnwKmt5btm1JnwTgVav1icreA2Kio
• abnormal immunoglobulin heavy chain V(D)J recombination_Pax5<tm1Mbu>/Pax5<tm1Mbu>
  http://metadb.riken.jp/0008760I129S2SvPasPax5tm1MbuPax5tm1MbuPax5tm1Mbu

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD06452
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD06452
• CD28362
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28362