decreased double-positive T cell number_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0005092IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis

decreased double-positive T cell number_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glucosidase, beta, acid
  http://metadb.riken.jp/db/mgi_rdf/MGI:95665
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Gba<tm1.1Pmis>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• Pramod K. Mistry, et.al., Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20962279