http://rdf.ncbi.nlm.nih.gov/pubmed/20962279

http://rdf.ncbi.nlm.nih.gov/pubmed/20962279

Pramod K. Mistry, et.al., Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gba<tm1.1Pmis>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4867659
• Gba<tm1.2Pmis>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4867660

class

http://purl.org/net/cito/citesAsAuthority

• Gba<tm1.1Pmis>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4867659
• Gba<tm1.2Pmis>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4867660

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased bone mineral density_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000063IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• decreased bone mineral density_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000063IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• abnormal trabecular bone morphology_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000130IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• abnormal trabecular bone morphology_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000130IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• kyphosis_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000160IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• kyphosis_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000160IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
他56件を見る
• decreased circulating HDL cholesterol level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000186IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• decreased circulating HDL cholesterol level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000186IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• extramedullary hematopoiesis_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000240IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• extramedullary hematopoiesis_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000240IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• enlarged liver_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000599IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• enlarged liver_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000599IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• enlarged spleen_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000691IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• enlarged spleen_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000691IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• spleen hyperplasia_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000693IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• spleen hyperplasia_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000693IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• abnormal thymus morphology_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000703IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• abnormal thymus morphology_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000703IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• decreased body size_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001265IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• decreased body size_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001265IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• abnormal skeleton physiology_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001533IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• abnormal skeleton physiology_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001533IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• abnormal T cell differentiation_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002145IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• abnormal T cell differentiation_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002145IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• decreased hemoglobin content_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002874IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• decreased hemoglobin content_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002874IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• increased liver weight_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002981IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• increased liver weight_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002981IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• pallor_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003717IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• pallor_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003717IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• decreased double-positive T cell number_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005092IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• decreased double-positive T cell number_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005092IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• increased circulating aspartate transaminase level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005343IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• increased circulating aspartate transaminase level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005343IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• abnormal osteoblast differentiation_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008395IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• abnormal osteoblast differentiation_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008395IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• decreased circulating tumor necrosis factor level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008554IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• decreased circulating tumor necrosis factor level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008554IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• increased circulating interferon-gamma level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008577IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• increased circulating interferon-gamma level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008577IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• increased circulating interleukin-10 level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008593IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• increased circulating interleukin-10 level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008593IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• decreased circulating interleukin-6 level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008597IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• decreased circulating interleukin-6 level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008597IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• increased circulating interleukin-2 level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008599IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• increased circulating interleukin-2 level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008599IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• increased circulating interleukin-13 level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008608IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• increased circulating interleukin-13 level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008608IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• increased circulating interleukin-3 level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008623IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• increased circulating interleukin-3 level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008623IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• increased circulating interleukin-9 level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008629IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• increased circulating interleukin-9 level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008629IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• decreased circulating interleukin-1 alpha level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008639IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• decreased circulating interleukin-1 alpha level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008639IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• decreased circulating interleukin-1 beta level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008642IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• decreased circulating interleukin-1 beta level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008642IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• abnormal circulating chemokine level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010209IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• abnormal circulating chemokine level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010209IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• abnormal circulating cytokine level_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010210IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• abnormal circulating cytokine level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010210IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis
• decreased bone ossification_Gba<tm1.1Pmis>/Gba<tm1.1Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0020040IC57BL6CBAGbatm11PmisGbatm11PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm11Pmis
• decreased bone ossification_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0020040IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD29608
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD29608