decreased B cell proliferation_Vav1<tm2Bbd>/Vav1<tm2Bbd>

http://metadb.riken.jp/0005093I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav1tm2Bbd

decreased B cell proliferation_Vav1<tm2Bbd>/Vav1<tm2Bbd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• vav 1 oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:98923

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Vav1<tm2Bbd>/Vav1<tm2Bbd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Vav1<tm2Bbd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B cell proliferation
  http://purl.obolibrary.org/obo/MP_0005093

文献

http://purl.org/net/cito/citesAsAuthority

• M F. Bachmann, et.al., The guanine-nucleotide exchange factor Vav is a crucial regulator of B cell receptor activation and B cell responses to nonrepetitive antigens., Journal of immunology (Baltimore, Md. : 1950), 1999, 163
  http://rdf.ncbi.nlm.nih.gov/pubmed/10384109
• K. Tedford, et.al., Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling., Nature immunology, 2001, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/11376343