K. Tedford, et.al., Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling., Nature immunology, 2001, 2

http://rdf.ncbi.nlm.nih.gov/pubmed/11376343

K. Tedford, et.al., Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling., Nature immunology, 2001, 2

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Vav2<tm1Kdf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387822

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased IgG1 level_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0008495I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• abnormal lymph node cell ratio_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0008828I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• abnormal T cell differentiation_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0002145I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• decreased CD8-positive, alpha-beta T cell number_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0008079I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• abnormal lymph node cell ratio_Vav1<tm2Bbd>/Vav1<tm2Bbd>
  http://metadb.riken.jp/0008828I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav1tm2Bbd
• decreased immunoglobulin level_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0002460I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• decreased IgM level_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0001806I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• abnormal B cell differentiation_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0002144I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• decreased IgG3 level_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0008498I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• decreased T cell number_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0005018I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• decreased B cell number_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0005017I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• decreased IgG3 level_Vav1<tm2Bbd>/Vav1<tm2Bbd>
  http://metadb.riken.jp/0008498I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav1tm2Bbd
• abnormal splenic cell ratio_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0008826I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• decreased B-1 B cell number_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0004978I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• decreased B cell proliferation_Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0005093I129S1SvC57BL6Vav2tm1KdfVav2tm1KdfVav2tm1Kdf
• decreased IgG3 level_Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0008498I129S1SvC57BL6Vav2tm1KdfVav2tm1KdfVav2tm1Kdf
• decreased mature B cell number_Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0008211I129S1SvC57BL6Vav2tm1KdfVav2tm1KdfVav2tm1Kdf
• decreased mature B cell number_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0008211I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• decreased IgG2b level_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0008497I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• abnormal splenic cell ratio_Vav1<tm2Bbd>/Vav1<tm2Bbd>
  http://metadb.riken.jp/0008826I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav1tm2Bbd
• decreased B cell proliferation_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0005093I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• increased transitional stage B cell number_Vav1<tm2Bbd>/Vav1<tm2Bbd>
  http://metadb.riken.jp/0008189I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav1tm2Bbd
• decreased B cell proliferation_Vav1<tm2Bbd>/Vav1<tm2Bbd>
  http://metadb.riken.jp/0005093I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav1tm2Bbd
• abnormal B cell activation_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0008217I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd
• thymus hypoplasia_Vav1<tm2Bbd>/Vav1<tm2Bbd>,Vav2<tm1Kdf>/Vav2<tm1Kdf>
  http://metadb.riken.jp/0001823I129S1Sv129X1SvJC57BL6Vav1tm2BbdVav1tm2BbdVav2tm1KdfVav2tm1KdfVav2tm1KdfVav1tm2Bbd

class

http://purl.org/net/cito/citesAsAuthority

• Vav2<tm1Kdf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387822