abnormal T cell proliferation_Arhgef12<tm1.1Wet>/Arhgef12<tm1.1Wet>,Tg(Lck-cre)548Jxm/0

http://metadb.riken.jp/0005094I129C57BL6CBAArhgef12tm11WetArhgef12tm11WetTgLckcre548Jxm0TgLckcre548JxmArhgef12tm11Wet

abnormal T cell proliferation_Arhgef12<tm1.1Wet>/Arhgef12<tm1.1Wet>,Tg(Lck-cre)548Jxm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Rho guanine nucleotide exchange factor (GEF) 12
  http://metadb.riken.jp/db/mgi_rdf/MGI:1916882
• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Arhgef12<tm1.1Wet>/Arhgef12<tm1.1Wet>,Tg(Lck-cre)548Jxm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Lck-cre)548Jxm|Arhgef12<tm1.1Wet>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell proliferation
  http://purl.obolibrary.org/obo/MP_0005094

文献

http://purl.org/net/cito/citesAsAuthority

• Susanne. Herroeder, et.al., Guanine nucleotide-binding proteins of the G12 family shape immune functions by controlling CD4+ T cell adhesiveness and motility., Immunity, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19409815