decreased T cell proliferation_Cd28<tm1Shr>/Cd28<tm1Shr>,Ctla4<tm1Shr>/Ctla4<tm1Shr>

http://metadb.riken.jp/0005095C129S4Cd28tm1ShrCtla4tm1ShrCd28tm1ShrCd28tm1ShrCtla4tm1ShrCtla4tm1ShrCtla4tm1ShrCd28tm1Shr

decreased T cell proliferation_Cd28<tm1Shr>/Cd28<tm1Shr>,Ctla4<tm1Shr>/Ctla4<tm1Shr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cytotoxic T-lymphocyte-associated protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88556
• CD28 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88327

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd28<tm1Shr>/Cd28<tm1Shr>,Ctla4<tm1Shr>/Ctla4<tm1Shr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctla4<tm1Shr>|Cd28<tm1Shr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• C.129S4-Cd28<tm1Shr> Ctla4<tm1Shr>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T cell proliferation
  http://purl.obolibrary.org/obo/MP_0005095

文献

http://purl.org/net/cito/citesAsAuthority

• D A. Mandelbrot, et.al., B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4., The Journal of clinical investigation, 2001, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/11285307