decreased T cell proliferation_Brca1<tm2Mak>/Brca1<tm2Mak>,Tg(Lck-cre)548Jxm/?,Tg(TcrLCMV)327Sdz/?

http://metadb.riken.jp/0005095I129P2OlaHsdC57BL6CBABrca1tm2MakBrca1tm2MakTgLckcre548JxmTgTcrLCMV327SdzTgLckcre548JxmBrca1tm2MakTgTcrLCMV327Sdz

decreased T cell proliferation_Brca1<tm2Mak>/Brca1<tm2Mak>,Tg(Lck-cre)548Jxm/?,Tg(TcrLCMV)327Sdz/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198
• breast cancer 1, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:104537
• transgene insertion 327, Birgit Ledermann
  http://metadb.riken.jp/db/mgi_rdf/MGI:2665109

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca1<tm2Mak>/Brca1<tm2Mak>,Tg(Lck-cre)548Jxm/?,Tg(TcrLCMV)327Sdz/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Lck-cre)548Jxm|Brca1<tm2Mak>|Tg(TcrLCMV)327Sdz

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T cell proliferation
  http://purl.obolibrary.org/obo/MP_0005095

文献

http://purl.org/net/cito/citesAsAuthority

• T W. Mak, et.al., Brca1 required for T cell lineage development but not TCR loci rearrangement., Nature immunology, 2000, 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/10881179