decreased T cell proliferation_Zap70<m1Saka>/Zap70<m1Saka>

http://metadb.riken.jp/0005095IBALBcZap70m1SakaZap70m1SakaZap70m1Saka

decreased T cell proliferation_Zap70<m1Saka>/Zap70<m1Saka>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• zeta-chain (TCR) associated protein kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99613

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Zap70<m1Saka>/Zap70<m1Saka>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Zap70<m1Saka>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T cell proliferation
  http://purl.obolibrary.org/obo/MP_0005095

文献

http://purl.org/net/cito/citesAsAuthority

• Noriko. Sakaguchi, et.al., Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice., Nature, 2003, 426
  http://rdf.ncbi.nlm.nih.gov/pubmed/14647385
• Lih-Yun. Hsu, et.al., A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity., The Journal of experimental medicine, 2009, 206
  http://rdf.ncbi.nlm.nih.gov/pubmed/19841086