decreased T cell proliferation_Lck<tm1Dbs>/Lck<tm1Dbs>,Tg(TcraTcrb)1100Mjb/0

http://metadb.riken.jp/0005095IC3HC57BL6Lcktm1DbsLcktm1DbsTgTcraTcrb1100Mjb0TgTcraTcrb1100MjbLcktm1Dbs

decreased T cell proliferation_Lck<tm1Dbs>/Lck<tm1Dbs>,Tg(TcraTcrb)1100Mjb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lymphocyte protein tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96756
• transgene insertion 1100, Michael J Bevan
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055219

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lck<tm1Dbs>/Lck<tm1Dbs>,Tg(TcraTcrb)1100Mjb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraTcrb)1100Mjb|Lck<tm1Dbs>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T cell proliferation
  http://purl.obolibrary.org/obo/MP_0005095

文献

http://purl.org/net/cito/citesAsAuthority

• Meghan L. Rudd, et.al., Lck SH3 domain function is required for T-cell receptor signals regulating thymocyte development., Molecular and cellular biology, 2006, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/16923964