Meghan L. Rudd, et.al., Lck SH3 domain function is required for T-cell receptor signals regulating thymocyte development., Molecular and cellular biology, 2006, 26

http://rdf.ncbi.nlm.nih.gov/pubmed/16923964

Meghan L. Rudd, et.al., Lck SH3 domain function is required for T-cell receptor signals regulating thymocyte development., Molecular and cellular biology, 2006, 26

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lck<tm1Dbs>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3690319

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• arrested T cell differentiation_Lck<tm1Dbs>/Lck<tm1Dbs>,Tg(TcraTcrb)425Cbn/0
  http://metadb.riken.jp/0001825IC3HC57BL6Lcktm1DbsLcktm1DbsTgTcraTcrb425Cbn0TgTcraTcrb425CbnLcktm1Dbs
• abnormal T cell differentiation_Lck<tm1Dbs>/Lck<tm1Dbs>
  http://metadb.riken.jp/0002145IC3HC57BL6Lcktm1DbsLcktm1DbsLcktm1Dbs
• abnormal positive T cell selection_Lck<tm1Dbs>/Lck<tm1Dbs>,Tg(TcraTcrb)1100Mjb/0
  http://metadb.riken.jp/0004919IC3HC57BL6Lcktm1DbsLcktm1DbsTgTcraTcrb1100Mjb0TgTcraTcrb1100MjbLcktm1Dbs
• decreased thymocyte number_Lck<tm1Dbs>/Lck<tm1Dbs>
  http://metadb.riken.jp/0000715IC3HC57BL6Lcktm1DbsLcktm1DbsLcktm1Dbs
• decreased T cell proliferation_Lck<tm1Dbs>/Lck<tm1Dbs>
  http://metadb.riken.jp/0005095IC3HC57BL6Lcktm1DbsLcktm1DbsLcktm1Dbs
• decreased T cell number_Lck<tm1Dbs>/Lck<tm1Dbs>
  http://metadb.riken.jp/0005018IC3HC57BL6Lcktm1DbsLcktm1DbsLcktm1Dbs
• abnormal CD4-positive, alpha beta T cell morphology_Lck<tm1Dbs>/Lck<tm1Dbs>
  http://metadb.riken.jp/0002432IC3HC57BL6Lcktm1DbsLcktm1DbsLcktm1Dbs
• abnormal T cell differentiation_Lck<tm1Dbs>/Lck<tm1Dbs>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0002145IC3HC57BL6DBA2JLcktm1DbsLcktm1DbsTgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboLcktm1Dbs
• arrested T cell differentiation_Lck<tm1Dbs>/Lck<tm1Dbs>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0001825IC3HC57BL6DBA2JLcktm1DbsLcktm1DbsTgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboLcktm1Dbs
• abnormal positive T cell selection_Lck<tm1Dbs>/Lck<tm1Dbs>,Tg(TcraTcrb)425Cbn/0
  http://metadb.riken.jp/0004919IC3HC57BL6Lcktm1DbsLcktm1DbsTgTcraTcrb425Cbn0TgTcraTcrb425CbnLcktm1Dbs
• decreased T cell proliferation_Lck<tm1Dbs>/Lck<tm1Dbs>,Tg(TcraTcrb)1100Mjb/0
  http://metadb.riken.jp/0005095IC3HC57BL6Lcktm1DbsLcktm1DbsTgTcraTcrb1100Mjb0TgTcraTcrb1100MjbLcktm1Dbs
• abnormal positive T cell selection_Lck<tm1Dbs>/Lck<tm1Dbs>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0004919IC3HC57BL6DBA2JLcktm1DbsLcktm1DbsTgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboLcktm1Dbs
• abnormal double-negative T cell morphology_Lck<tm1Dbs>/Lck<tm1Dbs>
  http://metadb.riken.jp/0002407IC3HC57BL6Lcktm1DbsLcktm1DbsLcktm1Dbs
• abnormal CD8-positive, alpha beta T cell morphology_Lck<tm1Dbs>/Lck<tm1Dbs>
  http://metadb.riken.jp/0005010IC3HC57BL6Lcktm1DbsLcktm1DbsLcktm1Dbs

class

http://purl.org/net/cito/citesAsAuthority

• Lck<tm1Dbs>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3690319