decreased circulating growth hormone level_Gt(ROSA)26Sor<tm1Fia>/Gt(ROSA)26Sor<+>,Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0

http://metadb.riken.jp/0005120I129S1Sv129X1SvJC57BL6CBAGtROSA26Sortm1FiaGtROSA26SorNf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0Nf1tm1ParGtROSA26Sortm1FiaTgFabp7crelacZ3GtmGtROSA26Sor

decreased circulating growth hormone level_Gt(ROSA)26Sor<tm1Fia>/Gt(ROSA)26Sor<+>,Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• neurofibromin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97306
• transgene insertion 3, David H Gutmann
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810646

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1Fia>/Gt(ROSA)26Sor<+>,Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nf1<tm1Par>|Gt(ROSA)26Sor<tm1Fia>|Tg(Fabp7-cre,-lacZ)3Gtm|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating growth hormone level
  http://purl.obolibrary.org/obo/MP_0005120

文献

http://purl.org/net/cito/citesAsAuthority

• Balazs. Hegedus, et.al., Neurofibromin regulates somatic growth through the hypothalamic-pituitary axis., Human molecular genetics, 2008, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/18614544