Balazs. Hegedus, et.al., Neurofibromin regulates somatic growth through the hypothalamic-pituitary axis., Human molecular genetics, 2008, 17

http://rdf.ncbi.nlm.nih.gov/pubmed/18614544

Balazs. Hegedus, et.al., Neurofibromin regulates somatic growth through the hypothalamic-pituitary axis., Human molecular genetics, 2008, 17

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating growth hormone level_Gt(ROSA)26Sor<tm1Fia>/Gt(ROSA)26Sor<+>,Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0005120I129S1Sv129X1SvJC57BL6CBAGtROSA26Sortm1FiaGtROSA26SorNf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0Nf1tm1ParGtROSA26Sortm1FiaTgFabp7crelacZ3GtmGtROSA26Sor
• decreased body weight_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJC57BL6CBANf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0TgFabp7crelacZ3GtmNf1tm1Par
• decreased circulating growth hormone level_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0005120I129S1Sv129X1SvJC57BL6CBANf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0TgFabp7crelacZ3GtmNf1tm1Par
• abnormal hypothalamus physiology_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0005645I129S1Sv129X1SvJC57BL6CBANf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0TgFabp7crelacZ3GtmNf1tm1Par
• abnormal hormone level_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0003953I129S1Sv129X1SvJC57BL6CBANf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0TgFabp7crelacZ3GtmNf1tm1Par
• decreased body weight_Gt(ROSA)26Sor<tm1Fia>/Gt(ROSA)26Sor<+>,Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJC57BL6CBAGtROSA26Sortm1FiaGtROSA26SorNf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0Nf1tm1ParGtROSA26Sortm1FiaTgFabp7crelacZ3GtmGtROSA26Sor
• abnormal pituitary gland development_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0003816I129S1Sv129X1SvJC57BL6CBANf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0TgFabp7crelacZ3GtmNf1tm1Par
• abnormal pituitary gland morphology_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0000633I129S1Sv129X1SvJC57BL6CBANf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0TgFabp7crelacZ3GtmNf1tm1Par
• postnatal growth retardation_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0001732I129S1Sv129X1SvJC57BL6CBANf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0TgFabp7crelacZ3GtmNf1tm1Par
• abnormal pituitary gland physiology_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0005646I129S1Sv129X1SvJC57BL6CBANf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0TgFabp7crelacZ3GtmNf1tm1Par
• small adenohypophysis_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0008321I129S1Sv129X1SvJC57BL6CBANf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0TgFabp7crelacZ3GtmNf1tm1Par
• small adenohypophysis_Gt(ROSA)26Sor<tm1Fia>/Gt(ROSA)26Sor<+>,Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0008321I129S1Sv129X1SvJC57BL6CBAGtROSA26Sortm1FiaGtROSA26SorNf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0Nf1tm1ParGtROSA26Sortm1FiaTgFabp7crelacZ3GtmGtROSA26Sor
• small pituitary gland_Nf1<tm1Par>/Nf1<tm1Par>,Tg(Fabp7-cre,-lacZ)3Gtm/0
  http://metadb.riken.jp/0005361I129S1Sv129X1SvJC57BL6CBANf1tm1ParNf1tm1ParTgFabp7crelacZ3Gtm0TgFabp7crelacZ3GtmNf1tm1Par