increased circulating thyroid-stimulating hormone level_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Tg-cre)1Soff/0

http://metadb.riken.jp/0005122I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgTgcre1Soff0Gna11tm1SoffGnaqtm2SoffTgTgcre1Soff

increased circulating thyroid-stimulating hormone level_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Tg-cre)1Soff/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• guanine nucleotide binding protein, alpha q polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:95776
• transgene insertion 1, Stefan Offermanns
  http://metadb.riken.jp/db/mgi_rdf/MGI:3796560
• guanine nucleotide binding protein, alpha 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:95766

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Tg-cre)1Soff/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gna11<tm1Soff>|Gnaq<tm2Soff>|Tg(Tg-cre)1Soff

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating thyroid-stimulating hormone level
  http://purl.obolibrary.org/obo/MP_0005122

文献

http://purl.org/net/cito/citesAsAuthority

• Jukka. Kero, et.al., Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development., The Journal of clinical investigation, 2007, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/17694176