decreased thyroid-stimulating hormone level_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(TPO-cre)1Shk/0

http://metadb.riken.jp/0005134129CgTrp53tm1BrnPtentm21PppTgTPOcre1ShkPtentm21PppPtentm21PppTrp53tm1BrnTrp53tm1BrnTgTPOcre1Shk0TgTPOcre1ShkTrp53tm1BrnPtentm21Ppp

decreased thyroid-stimulating hormone level_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(TPO-cre)1Shk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 1, Shioko Kimura
  http://metadb.riken.jp/db/mgi_rdf/MGI:3653643
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(TPO-cre)1Shk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TPO-cre)1Shk|Trp53<tm1Brn>|Pten<tm2.1Ppp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• 129.Cg-Trp53<tm1Brn> Pten<tm2.1Ppp> Tg(TPO-cre)1Shk

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased thyroid-stimulating hormone level
  http://purl.obolibrary.org/obo/MP_0005134

文献

http://purl.org/net/cito/citesAsAuthority

• Valeria G. Antico Arciuch, et.al., Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors., Oncotarget, 2011, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/22190384