Valeria G. Antico Arciuch, et.al., Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors., Oncotarget, 2011, 2

http://rdf.ncbi.nlm.nih.gov/pubmed/22190384

Valeria G. Antico Arciuch, et.al., Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors., Oncotarget, 2011, 2

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased thyroid carcinoma incidence_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0010346129CgTrp53tm1BrnPtentm21PppTgTPOcre1ShkPtentm21PppPtentm21PppTrp53tm1BrnTrp53tm1BrnTgTPOcre1Shk0TgTPOcre1ShkTrp53tm1BrnPtentm21Ppp
• enlarged thyroid gland_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0005355129CgTrp53tm1BrnPtentm21PppTgTPOcre1ShkPtentm21PppPtentm21PppTrp53tm1BrnTrp53tm1BrnTgTPOcre1Shk0TgTPOcre1ShkTrp53tm1BrnPtentm21Ppp
• premature death_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0002083129CgTrp53tm1BrnPtentm21PppTgTPOcre1ShkPtentm21PppPtentm21PppTrp53tm1BrnTrp53tm1BrnTgTPOcre1Shk0TgTPOcre1ShkTrp53tm1BrnPtentm21Ppp
• increased metastatic potential_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0001272129CgTrp53tm1BrnPtentm21PppTgTPOcre1ShkPtentm21PppPtentm21PppTrp53tm1BrnTrp53tm1BrnTgTPOcre1Shk0TgTPOcre1ShkTrp53tm1BrnPtentm21Ppp
• decreased thyroid-stimulating hormone level_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0005134129CgTrp53tm1BrnPtentm21PppTgTPOcre1ShkPtentm21PppPtentm21PppTrp53tm1BrnTrp53tm1BrnTgTPOcre1Shk0TgTPOcre1ShkTrp53tm1BrnPtentm21Ppp