cachexia_Col1a1<tm5(tetO-GFP/RNAi:Cdkn2a)Slowe>/Col1a1<+>,Gt(ROSA)26Sor<tm1(Luc)Kael>/Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>,Kras<tm4Tyj>/Kras<+>,Tg(Scgb1a1-rtTA)1Jaw/0

http://metadb.riken.jp/0005150I129S4SvJae129S6SvEvTacC57BL6Col1a1tm5tetOGFPRNAiCdkn2aSloweCol1a1GtROSA26Sortm1LucKaelGtROSA26Sortm1rtTAM2JaeKrastm4TyjKrasTgScgb1a1rtTA1Jaw0TgScgb1a1rtTA1JawGtROSA26Sortm1LucKaelCol1a1tm5tetOGFPRNAiCdkn2aSloweKrastm4TyjKrasCol1a1GtROSA26Sortm1rtTAM2Jae

cachexia_Col1a1<tm5(tetO-GFP/RNAi:Cdkn2a)Slowe>/Col1a1<+>,Gt(ROSA)26Sor<tm1(Luc)Kael>/Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>,Kras<tm4Tyj>/Kras<+>,Tg(Scgb1a1-rtTA)1Jaw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:2652186
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm5(tetO-GFP/RNAi:Cdkn2a)Slowe>/Col1a1<+>,Gt(ROSA)26Sor<tm1(Luc)Kael>/Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>,Kras<tm4Tyj>/Kras<+>,Tg(Scgb1a1-rtTA)1Jaw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Scgb1a1-rtTA)1Jaw|Gt(ROSA)26Sor<tm1(Luc)Kael>|Col1a1<tm5(tetO-GFP/RNAi:Cdkn2a)Slowe>|Kras<tm4Tyj>|Kras<+>|Col1a1<+>|Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cachexia
  http://purl.obolibrary.org/obo/MP_0005150

文献

http://purl.org/net/cito/citesAsAuthority

• Prem K. Premsrirut, et.al., A rapid and scalable system for studying gene function in mice using conditional RNA interference., Cell, 2011, 145
  http://rdf.ncbi.nlm.nih.gov/pubmed/21458673