cyclopia_Tg(Sox2-cre)1Amc/0,Tgif1<tm1Caw>/Tgif1<tm1Caw>,Tgif2<tm1Dwot>/Tgif2<tm1Dwot>

http://metadb.riken.jp/0005163I129SSvEvC57BL6C57BL6JCBATgSox2cre1Amc0Tgif1tm1CawTgif1tm1CawTgif2tm1DwotTgif2tm1DwotTgSox2cre1AmcTgif1tm1CawTgif2tm1Dwot

cyclopia_Tg(Sox2-cre)1Amc/0,Tgif1<tm1Caw>/Tgif1<tm1Caw>,Tgif2<tm1Dwot>/Tgif2<tm1Dwot>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• TGFB-induced factor homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1194497
• TGFB-induced factor homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1915299
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Sox2-cre)1Amc/0,Tgif1<tm1Caw>/Tgif1<tm1Caw>,Tgif2<tm1Dwot>/Tgif2<tm1Dwot>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Sox2-cre)1Amc|Tgif1<tm1Caw>|Tgif2<tm1Dwot>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6 * C57BL/6J * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• cyclopia
  http://purl.obolibrary.org/obo/MP_0005163

文献

http://purl.org/net/cito/citesAsAuthority

• Kenichiro. Taniguchi, et.al., Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway., PLoS genetics, 2012, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/22383895