eyelids fail to open_Klf4<tm1Khk>/Klf4<tm1Khk>,Klf5<tm1Jaw>/Klf5<tm1Jaw>,Tg(Pax6-cre,GFP)1Pgr/0

http://metadb.riken.jp/0005176I129S6SvEvTacFVBKlf4tm1KhkKlf4tm1KhkKlf5tm1JawKlf5tm1JawTgPax6creGFP1Pgr0Klf5tm1JawTgPax6creGFP1PgrKlf4tm1Khk

eyelids fail to open_Klf4<tm1Khk>/Klf4<tm1Khk>,Klf5<tm1Jaw>/Klf5<tm1Jaw>,Tg(Pax6-cre,GFP)1Pgr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Peter Gruss
  http://metadb.riken.jp/db/mgi_rdf/MGI:3045750
• Kruppel-like factor 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338056
• Kruppel-like factor 4 (gut)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342287

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Klf4<tm1Khk>/Klf4<tm1Khk>,Klf5<tm1Jaw>/Klf5<tm1Jaw>,Tg(Pax6-cre,GFP)1Pgr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Klf5<tm1Jaw>|Tg(Pax6-cre,GFP)1Pgr|Klf4<tm1Khk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• eyelids fail to open
  http://purl.obolibrary.org/obo/MP_0005176

文献

http://purl.org/net/cito/citesAsAuthority

• Doreswamy. Kenchegowda, et.al., Conditional disruption of mouse Klf5 results in defective eyelids with malformed meibomian glands, abnormal cornea and loss of conjunctival goblet cells., Developmental biology, 2011, 356
  http://rdf.ncbi.nlm.nih.gov/pubmed/21600198