decreased circulating estradiol level_Nhlh2<tm2Thbr>/Nhlh2<tm2Thbr>,Tg(CMV-cre)1Cgn/0

http://metadb.riken.jp/0005181I129S7SvEvBrdBALBcJC57BL6Nhlh2tm2ThbrNhlh2tm2ThbrTgCMVcre1Cgn0Nhlh2tm2ThbrTgCMVcre1Cgn

decreased circulating estradiol level_Nhlh2<tm2Thbr>/Nhlh2<tm2Thbr>,Tg(CMV-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nescient helix loop helix 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97324
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176179

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nhlh2<tm2Thbr>/Nhlh2<tm2Thbr>,Tg(CMV-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nhlh2<tm2Thbr>|Tg(CMV-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * BALB/cJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating estradiol level
  http://purl.obolibrary.org/obo/MP_0005181

文献

http://purl.org/net/cito/citesAsAuthority

• Thomas. Schmid, et.al., Loss of NSCL-2 in gonadotropin releasing hormone neurons leads to reduction of pro-opiomelanocortin neurons in specific hypothalamic nuclei and causes visceral obesity., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/23785158