abnormal iris stroma morphology_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)2Pgr/0

http://metadb.riken.jp/0005208I129S1Sv129X1SvJPax6tm2PgrPax6TgPax6creGFP2Pgr0Pax6tm2PgrPax6TgPax6creGFP2Pgr

abnormal iris stroma morphology_Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)2Pgr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• paired box 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:97490
• transgene insertion 2, Peter Gruss
  http://metadb.riken.jp/db/mgi_rdf/MGI:3052668

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pax6<tm2Pgr>/Pax6<+>,Tg(Pax6-cre,GFP)2Pgr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pax6<tm2Pgr>|Pax6<+>|Tg(Pax6-cre,GFP)2Pgr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal iris stroma morphology
  http://purl.obolibrary.org/obo/MP_0005208

文献

http://purl.org/net/cito/citesAsAuthority

• Markus. Kroeber, et.al., Reduced expression of Pax6 in lens and cornea of mutant mice leads to failure of chamber angle development and juvenile glaucoma., Human molecular genetics, 2010, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/20538882