abnormal pancreatic beta cell morphology_Pdx1<tm1Cvw>/Pdx1<+>,Spop<Gt(BGB118)Byg>/Spop<+>

http://metadb.riken.jp/0005217I129P2OlaHsd129S1Sv129X1SvJC57BL6Pdx1tm1CvwPdx1SpopGtBGB118BygSpopPdx1SpopPdx1tm1CvwSpopGtBGB118Byg

abnormal pancreatic beta cell morphology_Pdx1<tm1Cvw>/Pdx1<+>,Spop<Gt(BGB118)Byg>/Spop<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• speckle-type POZ protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:1343085
• pancreatic and duodenal homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:102851

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pdx1<tm1Cvw>/Pdx1<+>,Spop<Gt(BGB118)Byg>/Spop<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pdx1<+>|Spop<+>|Pdx1<tm1Cvw>|Spop<Gt(BGB118)Byg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreatic beta cell morphology
  http://purl.obolibrary.org/obo/MP_0005217

文献

http://purl.org/net/cito/citesAsAuthority

• Kathryn C. Claiborn, et.al., Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20811152