abnormal pancreatic beta cell morphology_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>,Tg(Ins2-Akt1*)3Mbb/0

http://metadb.riken.jp/0005217I129P2OlaHsdC57BL6SJLRps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoTgIns2Akt13Mbb0TgIns2Akt13MbbRps6kb1tm1GthoRps6kb2tm1Gtho

abnormal pancreatic beta cell morphology_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>,Tg(Ins2-Akt1*)3Mbb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 3, Morris J Birnbaum
  http://metadb.riken.jp/db/mgi_rdf/MGI:5829192
• ribosomal protein S6 kinase, polypeptide 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927343
• ribosomal protein S6 kinase, polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1270849

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>,Tg(Ins2-Akt1*)3Mbb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-Akt1*)3Mbb|Rps6kb1<tm1Gtho>|Rps6kb2<tm1Gtho>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreatic beta cell morphology
  http://purl.obolibrary.org/obo/MP_0005217

文献

http://purl.org/net/cito/citesAsAuthority

• Samira. Alliouachene, et.al., Constitutively active Akt1 expression in mouse pancreas requires S6 kinase 1 for insulinoma formation., The Journal of clinical investigation, 2008, 118
  http://rdf.ncbi.nlm.nih.gov/pubmed/18846252