abnormal pancreatic beta cell morphology_Gsk3b<tm1Jrw>/Gsk3b<+>,Irs2<tm1Mfw>/Irs2<tm1Mfw>

http://metadb.riken.jp/0005217I129S1Sv129X1SvJC57BL6JGsk3btm1JrwGsk3bIrs2tm1MfwIrs2tm1MfwGsk3btm1JrwGsk3bIrs2tm1Mfw

abnormal pancreatic beta cell morphology_Gsk3b<tm1Jrw>/Gsk3b<+>,Irs2<tm1Mfw>/Irs2<tm1Mfw>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glycogen synthase kinase 3 beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861437
• insulin receptor substrate 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109334

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gsk3b<tm1Jrw>/Gsk3b<+>,Irs2<tm1Mfw>/Irs2<tm1Mfw>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gsk3b<tm1Jrw>|Gsk3b<+>|Irs2<tm1Mfw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreatic beta cell morphology
  http://purl.obolibrary.org/obo/MP_0005217

文献

http://purl.org/net/cito/citesAsAuthority

• Katsuya. Tanabe, et.al., Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance., PLoS biology, 2008, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/18288891