abnormal pancreatic beta cell morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0005217I129S4SvJae129S6SvEvTacBALBcC57BL6DBAPtentm1HwuPtentm1HwuRictortm11MgnRictortm11MgnTgIns2cre25Mgn0Ptentm1HwuRictortm11MgnTgIns2cre25Mgn

abnormal pancreatic beta cell morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• RPTOR independent companion of MTOR, complex 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926007
• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<tm1Hwu>,Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Hwu>|Rictor<tm1.1Mgn>|Tg(Ins2-cre)25Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S6/SvEvTac * BALB/c * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreatic beta cell morphology
  http://purl.obolibrary.org/obo/MP_0005217

文献

http://purl.org/net/cito/citesAsAuthority

• Yanyun. Gu, et.al., Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size., Diabetes, 2011, 60
  http://rdf.ncbi.nlm.nih.gov/pubmed/21266327