Yanyun. Gu, et.al., Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size., Diabetes, 2011, 60

http://rdf.ncbi.nlm.nih.gov/pubmed/21266327

Yanyun. Gu, et.al., Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size., Diabetes, 2011, 60

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased pancreatic beta cell mass_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009113I129S4SvJaeBALBcC57BL6DBAPtentm1HwuPtentm1HwuTgIns2cre25Mgn0Ptentm1HwuTgIns2cre25Mgn
• abnormal pancreatic beta cell morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005217I129S4SvJaeBALBcC57BL6DBAPtentm1HwuPtentm1HwuTgIns2cre25Mgn0Ptentm1HwuTgIns2cre25Mgn
• decreased circulating insulin level_Pten<tm1Hwu>/Pten<tm1Hwu>,Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002727I129S4SvJae129S6SvEvTacBALBcC57BL6DBAPtentm1HwuPtentm1HwuRictortm11MgnRictortm11MgnTgIns2cre25Mgn0Ptentm1HwuRictortm11MgnTgIns2cre25Mgn
• abnormal glucose homeostasis_Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002078I129S6SvEvTacBALBcC57BL6DBARictortm11MgnRictortm11MgnTgIns2cre25Mgn0TgIns2cre25MgnRictortm11Mgn
• impaired glucose tolerance_Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293I129S6SvEvTacBALBcC57BL6DBARictortm11MgnRictortm11MgnTgIns2cre25Mgn0TgIns2cre25MgnRictortm11Mgn
• hypoglycemia_Pten<tm1Hwu>/Pten<tm1Hwu>,Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0000189I129S4SvJae129S6SvEvTacBALBcC57BL6DBAPtentm1HwuPtentm1HwuRictortm11MgnRictortm11MgnTgIns2cre25Mgn0Ptentm1HwuRictortm11MgnTgIns2cre25Mgn
• hyperglycemia_Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001559I129S6SvEvTacBALBcC57BL6DBARictortm11MgnRictortm11MgnTgIns2cre25Mgn0TgIns2cre25MgnRictortm11Mgn
• abnormal pancreatic beta cell morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005217I129S4SvJae129S6SvEvTacBALBcC57BL6DBAPtentm1HwuPtentm1HwuRictortm11MgnRictortm11MgnTgIns2cre25Mgn0Ptentm1HwuRictortm11MgnTgIns2cre25Mgn
• postnatal growth retardation_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001732I129S4SvJaeBALBcC57BL6DBAPtentm1HwuPtentm1HwuTgIns2cre25Mgn0Ptentm1HwuTgIns2cre25Mgn
• decreased insulin secretion_Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003059I129S6SvEvTacBALBcC57BL6DBARictortm11MgnRictortm11MgnTgIns2cre25Mgn0TgIns2cre25MgnRictortm11Mgn
• decreased pancreatic beta cell proliferation_Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0011820I129S6SvEvTacBALBcC57BL6DBARictortm11MgnRictortm11MgnTgIns2cre25Mgn0TgIns2cre25MgnRictortm11Mgn
• abnormal glucose homeostasis_Pten<tm1Hwu>/Pten<tm1Hwu>,Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002078I129S4SvJae129S6SvEvTacBALBcC57BL6DBAPtentm1HwuPtentm1HwuRictortm11MgnRictortm11MgnTgIns2cre25Mgn0Ptentm1HwuRictortm11MgnTgIns2cre25Mgn
• abnormal pancreatic beta cell physiology_Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003562I129S6SvEvTacBALBcC57BL6DBARictortm11MgnRictortm11MgnTgIns2cre25Mgn0TgIns2cre25MgnRictortm11Mgn
• decreased pancreatic beta cell mass_Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009114I129S6SvEvTacBALBcC57BL6DBARictortm11MgnRictortm11MgnTgIns2cre25Mgn0TgIns2cre25MgnRictortm11Mgn
• postnatal growth retardation_Pten<tm1Hwu>/Pten<tm1Hwu>,Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001732I129S4SvJae129S6SvEvTacBALBcC57BL6DBAPtentm1HwuPtentm1HwuRictortm11MgnRictortm11MgnTgIns2cre25Mgn0Ptentm1HwuRictortm11MgnTgIns2cre25Mgn
• decreased pancreatic beta cell mass_Pten<tm1Hwu>/Pten<tm1Hwu>,Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009114I129S4SvJae129S6SvEvTacBALBcC57BL6DBAPtentm1HwuPtentm1HwuRictortm11MgnRictortm11MgnTgIns2cre25Mgn0Ptentm1HwuRictortm11MgnTgIns2cre25Mgn