abnormal rostral-caudal axis patterning_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>

http://metadb.riken.jp/0005221I129S1Sv129X1SvJC57BL6GtROSA26Sortm1DTAMrcGtROSA26SorChrna7tm21creSwrChrna7Chrna7tm21creSwrGtROSA26Sortm1DTAMrcChrna7GtROSA26Sor

abnormal rostral-caudal axis patterning_Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cholinergic receptor, nicotinic, alpha polypeptide 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:99779
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(DTA)Mrc>/Gt(ROSA)26Sor<+>,Chrna7<tm2.1(cre)Swr>/Chrna7<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Chrna7<tm2.1(cre)Swr>|Gt(ROSA)26Sor<tm1(DTA)Mrc>|Chrna7<+>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal rostral-caudal axis patterning
  http://purl.obolibrary.org/obo/MP_0005221

文献

http://purl.org/net/cito/citesAsAuthority

• Scott W. Rogers, et.al., Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure., American journal of medical genetics. Part A, 2012, 158A
  http://rdf.ncbi.nlm.nih.gov/pubmed/22473653