impaired glucose tolerance_Apob<tm2Sgy>/Apob<tm2Sgy>,Apoe<tm1Unc>/Apoe<tm1Unc>,Lep<ob>/Lep<ob>

http://metadb.riken.jp/0005293I129P2OlaHsd129S7SvEvBrdC57BL6Apobtm2SgyApobtm2SgyApoetm1UncApoetm1UncLepobLepobLepobApoetm1UncApobtm2Sgy

impaired glucose tolerance_Apob<tm2Sgy>/Apob<tm2Sgy>,Apoe<tm1Unc>/Apoe<tm1Unc>,Lep<ob>/Lep<ob>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• apolipoprotein B
  http://metadb.riken.jp/db/mgi_rdf/MGI:88052
• leptin
  http://metadb.riken.jp/db/mgi_rdf/MGI:104663
• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apob<tm2Sgy>/Apob<tm2Sgy>,Apoe<tm1Unc>/Apoe<tm1Unc>,Lep<ob>/Lep<ob>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lep<ob>|Apoe<tm1Unc>|Apob<tm2Sgy>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired glucose tolerance
  http://purl.obolibrary.org/obo/MP_0005293

文献

http://purl.org/net/cito/citesAsAuthority

• David J. Lloyd, et.al., Generation and characterization of two novel mouse models exhibiting the phenotypes of the metabolic syndrome: Apob48-/-Lepob/ob mice devoid of ApoE or Ldlr., American journal of physiology. Endocrinology and metabolism, 2008, 294
  http://rdf.ncbi.nlm.nih.gov/pubmed/18160459