impaired glucose tolerance_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Pdx1-cre)89.1Dam/0

http://metadb.riken.jp/0005293I129S6SvEvTacC57BL6CBAStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgPdx1cre891Dam0Stat5btm1MamTgPdx1cre891DamStat5atm2Mam

impaired glucose tolerance_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Pdx1-cre)89.1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal transducer and activator of transcription 5A
  http://metadb.riken.jp/db/mgi_rdf/MGI:103036
• signal transducer and activator of transcription 5B
  http://metadb.riken.jp/db/mgi_rdf/MGI:103035
• transgene insertion 89.1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684318

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Pdx1-cre)89.1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stat5b<tm1Mam>|Tg(Pdx1-cre)89.1Dam|Stat5a<tm2Mam>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired glucose tolerance
  http://purl.obolibrary.org/obo/MP_0005293

文献

http://purl.org/net/cito/citesAsAuthority

• Ji-Yeon. Lee, et.al., The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging., Biochimica et biophysica acta, 2007, 1773
  http://rdf.ncbi.nlm.nih.gov/pubmed/17599554