Ji-Yeon. Lee, et.al., The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging., Biochimica et biophysica acta, 2007, 1773

http://rdf.ncbi.nlm.nih.gov/pubmed/17599554

Ji-Yeon. Lee, et.al., The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging., Biochimica et biophysica acta, 2007, 1773

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired glucose tolerance_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005293I129S6SvEvTacC57BL6CBAStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgPdx1cre891Dam0Stat5btm1MamTgPdx1cre891DamStat5atm2Mam
• increased circulating free fatty acid level_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001554I129S6SvEvTacC57BL6DBAStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5btm1MamTgIns2cre25Mgn
• impaired glucose tolerance_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005293I129S6SvEvTacC57BL6CBAStat5btm1MamStat5btm1MamTgPdx1cre891Dam0TgPdx1cre891DamStat5btm1Mam
• disorganized pancreatic islets_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009254I129S6SvEvTacC57BL6CBAStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgPdx1cre891Dam0Stat5btm1MamTgPdx1cre891DamStat5atm2Mam
• decreased insulin secretion_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003059I129S6SvEvTacC57BL6DBAStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5btm1MamTgIns2cre25Mgn
• impaired glucose tolerance_Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293IC57BL6DBATgIns2cre25Mgn0TgIns2cre25Mgn
• increased circulating free fatty acid level_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001554I129S6SvEvTacC57BL6DBAStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5atm2MamTgIns2cre25MgnStat5btm1Mam
• increased circulating leptin level_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005669I129S6SvEvTacC57BL6DBAStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5btm1MamTgIns2cre25Mgn
• obese_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001261I129S6SvEvTacC57BL6DBAStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5atm2MamTgIns2cre25MgnStat5btm1Mam
• obese_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001261I129S6SvEvTacC57BL6DBAStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5btm1MamTgIns2cre25Mgn
• decreased insulin secretion_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003059I129S6SvEvTacC57BL6DBAStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5atm2MamTgIns2cre25MgnStat5btm1Mam
• increased circulating glucose level_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005559I129S6SvEvTacC57BL6DBAStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5atm2MamTgIns2cre25MgnStat5btm1Mam
• increased total body fat amount_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0010024I129S6SvEvTacC57BL6DBAStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5btm1MamTgIns2cre25Mgn
• increased total body fat amount_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0010024I129S6SvEvTacC57BL6DBAStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5atm2MamTgIns2cre25MgnStat5btm1Mam
• disorganized pancreatic islets_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009254I129S6SvEvTacC57BL6CBAStat5btm1MamStat5btm1MamTgPdx1cre891Dam0TgPdx1cre891DamStat5btm1Mam
• disorganized pancreatic islets_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009254I129S6SvEvTacC57BL6DBAStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5atm2MamTgIns2cre25MgnStat5btm1Mam
• impaired glucose tolerance_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293I129S6SvEvTacC57BL6DBAStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5atm2MamTgIns2cre25MgnStat5btm1Mam
• impaired glucose tolerance_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293I129S6SvEvTacC57BL6DBAStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5btm1MamTgIns2cre25Mgn
• increased circulating leptin level_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005669I129S6SvEvTacC57BL6DBAStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5atm2MamTgIns2cre25MgnStat5btm1Mam
• disorganized pancreatic islets_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009254I129S6SvEvTacC57BL6DBAStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5btm1MamTgIns2cre25Mgn
• decreased insulin secretion_Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003059IC57BL6DBATgIns2cre25Mgn0TgIns2cre25Mgn
• increased circulating glucose level_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005559I129S6SvEvTacC57BL6DBAStat5btm1MamStat5btm1MamTgIns2cre25Mgn0Stat5btm1MamTgIns2cre25Mgn